Cell Fusion C     Cell Fusion Canada



CMS is a skin care line that stands for Cell Membrane Structure with products that help to provide a barrier that keeps irritants out and moisture in by using nanotechnology.

CMS restores healthy skin barrier functions and enhances anti-oxidant defense against photo-aging and free radical damage by delivering ingredients that mimic the intercellular lipid layers of the skin.

CMS uses nanotechnology and dual liposome techniques that have been clinically proven to effectively deliver active ingredients deep into the skin without chemical preservatives, mineral oil, fragrances and artificial dyes.

CMS carries a total 110 products – a retail line that consists of 58 products and a professional line that consists of 52 products.

CMS is available exclusively through doctors and licensed skin care professionals throughout 3, 800 cosmetic medical facilities in S. Korea and 18,000 doctors' offices worldwide throughout 22 countries including UK, USA, Canada, The Netherlands, Belgium, Switzerland, Sweden, Denmark, Norway, Spain, Ukraine, Belarus, Russia, Middle East, Malaysia, Japan, Hong Kong, Singapore, Poland, Philippines and Australia.
Preserving the skin barrier and the individually varying natural TEWL (Trans-Epidermal Water Loss) basically is the principal aim of skin care. Generally, within a period of about 4 weeks, the skin goes through a complete renewal process. Also, there is a certain loss of substances due to abrasions and peeling which has to be replaced. In addition to that, the skin loses basic substances through the solvent effect of liquids. Soaps and cleansing agents wash the natural fatty substances and acids out of the skin and thus form holes in the structure of the skins barrier layers. Unless skin care products are used on a regular base, the skin feels drier. The emulsifiers contained in skin care products also show wash out effects which generally are only realized on second sight. Emulsifiers stabilize mixtures of oils and water in the form of emulsions. With the application of emulsions the fatty
substances are transported into the skin. After the water has evaporated, most of the emulsifiers stay in the skin and will not degrade. The contact with water while showering or partially cleansing the skin reactivates the emulsifiers which then again transport fatty substances out of the skin with the result that the skin will not only lose skin care substances but also natural barrier substances.
It strongly reduces the TEWL rate and the natural skin regeneration will decrease. The stratum corneum is structured like brickwork. The dead cells are the "bricks" in this picture. The "mortar" which keeps the cells together consists of highly effective barrier layers with a bi-layer membrane structure similar to the cell membranes. They are also called lipid bi-layers. In cases where the membrane structure is disturbed the skin dehydrates, and due to its increased roughness or developed cracks, it is even more susceptible to the penetration of harmful substances. The objective of recent concepts is to keep the membrane structures between the cells in a rather natural and intact condition. This type of skin care has components which are very well tolerated by the natural membrane structure and which are able to restore it without impeding the natural regeneration of the skin. In this connection two factors are very important.

The skin is mainly comprised of three layers-the epidermis, dermis, and fat layer (also called the subcutaneous layer). The epidermis is relatively waterproof and protects the body from most bacteria, viruses, UV rays and other foreign substances. Damage to the epidermis significantly decreases the skin's protective function and can lead to skin troubles such as acne, atopic dermatitis, hyperpigmentation and premature aging. The stratum corneum, the outermost layer of the epidermis, plays a major role in maintaining the barrier properties of the skin. The permeability of the skin, water retention and protection of skin are dependent on the structure of the intercellular spaces which consist of hydrophobic lipids arranged as lamellar bilayers. Damage to the intercellular lipids gradually destroy the barrier system and damage cellular functions, enzymes and DNA in the skin, also resulting in increased T.E.W.L.

CMS products are developed specifically to prevent and repair intercellular damage in the skin. Ingredients such as ceramide, cholesterol, fatty acids, squalene, cholesteryl ester and triglycerides are the basis for CMS advanced formulations that optimize the skin's barrier function

CMS Nano Particle Cream does not contain any substances that may irritate the skin.
This cream contains the most similar substance to the phosphor lipid of the skin cell barrier including Phosphotidycholine, Ceramide, Triglyceride, Squalane, and Phytosterols . About 30 kinds of activating substances penetrate deeply into the skin with dual liposome processes to restore any damaged, aged, and sensitive skins. The liposome which is located on the outer most side of the dual liposome forms preservative on the biological membrane of skin cells and protects the skin barrier function
Structures of corneous cells and lipid barriers are formed as the "Brick and Mortar" figure. This model produces a function called the "Skin Barrier Function" which is paramount to the skin.
Skin Barrier Function
Main function of the Stratum Corneum: Prevents bacteria from penetrating the skin. Prevents the loss of water or electrolyte from the body. Produces elasticity and softness for hydration.
Breakdowns and Blockages of the Skin Barrier Function
Epidermal lipids constitute the lamellastacks of lipid bi-layers seen by infrared spectroscopy. Rather than the Stratum Corneum mass being less than 10% epidermal lipid efficiently create an effective skin barrier function
Structure of Lipid Barrier in the Stratum Corneum
If there is a break down of a skin barrier function the another Bacteria can easily penetrate the skin resulting in dehydration. As a result , sensitive, dry, of rematurely aged skin, atrophy and pigmentation may grow worse.



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